Table 3.

Bivariate^a and multivariate analysis^a of the association between mental illness (MI) and illicit drug use (DU) and virological suppression among HIV infected individuals on HAART (n = 8378)

	Virological suppression odds ratio (95% confidence interval)		Virological suppression adjusted odds ratio (95% confidence interval)
Characteristic	Bivariate analysis	p-Value	Multivariate	p-Value
Category
MI & DU	0.67 (0.57-0.79)	<0.01	0.66 (0.58-0.75)	<0.01
DU	0.78 (0.66-0.92)	<0.01	0.77 (0.67-0.88)	<0.01
MI	0.84(0.76-0.93)	<0.01	0.93 (0.82-1.05)	0.24
Neither MI nor DU	1.00 (referent)		1.00 (referent)
Age (years)
≥45	1.89 (1.67-2.14)	<0.01	2.07 (1.87-2.37)	<0.01
>35 & <45	1.41 (1.25-1.60)	<0.01	1.49 (1.39-1.70)	<0.02
≤35	1.00 (referent)		1.00 (referent)
Gender
Male	1.12 (1.00-1.23)	0.06	0.99 (0.89-1.12)	0.98
Female	1.00 (referent)		1.00 (referent)
Race/Ethnicity
Black/African American	0.74 (0.66-0.83)	<0.01	0.81 (0.72-0.91)	<0.01
Hispanic	0.89 (0.79-1.01)	0.08	1.03 (0.90-1.18)	0.50
Other	1.42 (1.06-1.90)	0.02	1.46 (1.08-1.98)	0.01
White/Caucasian	1.00 (referent)		1.00 (referent)
CD4 count (cells/mm3)
>200	1.87 (1.70-2.05)	<0.01	1.89 (1.71-2.07)	<0.01
≤200	1.00 (referent)		1.00 (referent)
Outpatient medical visits during calendar year 2004
≥7	0.51 (0.45-0.57)	<0.01	0.52 (0.46-0.59)	<0.01
4-6	0.88 (0.78-0.98)	0.02	0.87 (0.78-0.98)	0.02
<4	1.00 (referent)		1.00 (referent)
Years in clinical care	1.03 (1.02-1.05)		1.03 (1.02-1.05)	<0.01

^aAnalysis adjusted for site.