Table 3.
A Comparison of subjects with AG with and without dementia
AG with dementia (N=8) | AG without dementia (N=14) | P value | |
---|---|---|---|
Female gender | 4 (50%) | 10 (71%) | ns |
*Age at onset of dementia | 87 years (73–97) | n/a | n/a |
*MMSE score prior to death | 20.5 (5–28) | 28 (22–30) | 0.002 |
*Age at death | 90.5 years (77–100) | 89.5 years (74–101) | ns |
*Braak stage | 4 (3–4) | 3 (0–4) | 0.02 |
Number of subjects with Braak stage ≤ 2 | 0 (0%) | 5 (36%) | ns |
Number of subjects that fulfilled Khachaturian criteria | 5 (63%) | 8 (57%) | ns |
Number of subjects that fulfilled CERAD criteria - C | 0 (0%) | 0 (0%) | ns |
Number of subjects that fulfilled CERAD criteria – B | 2 (25%) | 0 (0%) | ns |
Number of subjects that fulfilled CERAD criteria - A | 5 (63%) | 5 (38%) | ns |
βNumber of subjects that fulfilled CERAD criteria - 0 | 1 (13%) | 9 (64%) | 0.03 |
Number of subjects that fulfilled NIA-Reagan criteria for AD | 0 (0%) | 0 (0%) | ns |
ns = not significant, n/a = not applicable; MMSE = Mini-mental State Examination
Values shown are medians (range)
Not significant after adjusting for multiple comparisons