Skip to main content
. Author manuscript; available in PMC: 2009 Aug 17.
Published in final edited form as: Adv Biochem Eng Biotechnol. 2007;104:65–85. doi: 10.1007/10_025

Figure 5. Identification of the DNA binding site motif from the significantly bound spots.

Figure 5

Figure 5

(a) Distribution of ratios of PBM data, normalized by SYBR Green I data, for the yeast TF Rap1 bound to yeast intergenic microarrays. The arrow indicates those spots passing a P-value cutoff of 0.001 after correction for multiple hypothesis testing. Indicated in dark gray are spots with an exact match to a sequence belonging to the PBM-derived binding site motif. (b) Sequence logo [53] of the PBM-derived motif for the yeast TF Rap1. (Reproduced from [26] with permission from Nature Publishing Group.)