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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Clin Cancer Res. 2009 Apr 7;15(8):2630–2636. doi: 10.1158/1078-0432.CCR-08-2592

Table 3.

Summary of detecting EGFR-activating mutations from plasma DNA

Plasma DNA
Mutation No Mutation
Tumor tissue
Mutation 30 21 9
No mutation 13 2 11
Not available 11 6 5
Response to prior EGFR TKI therapy
Partial response 28 23 5
Stable disease 14 4 10
Progressive disease 8 2 6
Untreated 4 0 4

NOTE: NSCLC patients broken down based on known tumor EGFR mutations and based on clinical outcome with prior EGFR TKI therapy.