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Activation of caspases 3 and 8 in SK-N-AS neuroblastoma cells following treatment with CDDO-Me. (A) dose-dependence after 6 h exposure to 0–250 nM of CDDO-Me; (B) time-courses 0–24 h of caspases 3 and 8 activation by 250 nM CDDO-Me. Experiments were performed in triplicate. Error bars represent standard errors of means for each point. AMC: 7-amino-4-methoxy coumarin.
