. Author manuscript; available in PMC: 2010 Jul 29.

Published in final edited form as: J Am Chem Soc. 2009 Jul 29;131(29):9886–9887. doi: 10.1021/ja903573p

Table 1.

Directing Group Screening^a,^b


X = OMe a 0% b 0%	a 3% b 0%	a 0% b 0%	a 12% b 0%	a 10% b 0%
a 24% b 12%		a 18% b 8%	a 30% b 22%	a 34% b 54%

Conditions: 0.2 mmol of substrate, 10 mol% Pd(OAc)₂, 20 mol% ligand, 3.0 equiv of CsF, 3.0 equiv of aryl iodide, 100 mg 3Å MS, 1 mL toluene, 100 °C, N₂, 24 h.

Yield was determined by ¹H NMR analysis of crude product using CH₂Br₂ as the internal standard.