Table 2. Most up and down-regulated transcripts derived from the comparison C99V50F/C99WT1 (Aβ₄₂/Aβ₄₀↓).

Position	Probe set ID	p-value	Fold change C99V50F/C99WT1 Aβ42/Aβ40↓	Gene symbol	Gene title	Chromo-somal location
1	206478_at	0.00142	5.3	KIAA0125	KIAA0125	chr14q32.33
2	208603_s_at	0.00191	2.5	MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	chr22q13.33
3	200974_at	0.00115	2.2	ACTA2	actin, alpha 2, smooth muscle, aorta	chr10q23.3
4	216963_s_at	0.00449	2.2	GAP43	growth associated protein 43	chr3q13.1-q13.2
5	201860_s_at	0.00477	2.1	PLAT	plasminogen activator, tissue	chr8p12
6	206397_x_at	0.00269	2.1	GDF1	growth differentiation factor 1	chr19p12
7	204471_at	0.00190	2.1	GAP43	growth associated protein 43	chr3q13.1-q13.2
7	220287_at	0.00110	−2.0	ADAMTS9	a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9	chr3p14.3-p14.2
6	209220_at	0.00089	−2.5	GPC3	glypican 3	chrxq26.1
5	212148_at	0.00288	−2.8	PBX1	pre-B-cell leukemia transcription factor 1	chr1q23
4	209757_s_at	0.00416	−3.0	MYCN	v-myc myelocytomatosis viral relatedoncogene, neuroblastoma derived (avian)	chr2p24.1
3	202283_at	0.00362	−3.1	SERPINF1	serine proteinase inhibitor,clade F (alpha-2 antiplasmin, pigmentepithelium derived factor), member 1	chr17p13.1
2	209238_at	0.00268	−3.7	STX3A	syntaxin 3A	chr11q12.1
1	215632_at	0.00166	−12.5	NEUROG2	neurogenin 2	chr4q25

Table 2 Most up and down-regulated transcripts derived from the comparison C99V50F/C99WT1 (Aβ₄₂/Aβ₄₀↓; n = 3 per group; p < 0.005, unadjusted p-values; C99WT1 was the baseline experiment). The unspliced GAP43 and its spliced isoform were detected by two different probe sets (204471_at and 216963_s_at).