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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Cancer Res. 2009 Jul 14;69(15):6355–6363. doi: 10.1158/0008-5472.CAN-09-1195

Figure 2. Overexpression of EcSOD increased the inhibitory effects of heparin/LMWH on breast cancer cell growth and clonogenic capacity.

Figure 2

(A and C) Cells were infected with adenovirus vectors in complete media or media supplemented with heparin/LMWH and cell doubling times were calculated from the growth curves as described in Materials and Methods. (B and D) The colony forming ability of cells was evaluated by counting colonies 14 days post seeding. Inhibition of heparanase expression was achieved via siHPSE transfection. Non-targeting siNegative was used as a siRNA transfection control. Error bars = SD of the mean of three growth curves. Using one way ANOVA followed by post-hoc Tukey's test, *P <0.05 vs. AdEmpty, ** P <0.05 vs. LMWH plus AdEmpty, # P<0.01 vs. siNegative transfection.