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Tumor incidence of transformed HMLEs induced to undergo EMT by ectopic expression of Snail or Twist and then injected into host mice in limiting dilutions.
| Cells injected |
Tumors incidence/number of injections |
|||
|---|---|---|---|---|
| 1×106 | 1×105 | 1×104 | 1×103 | |
| HMLE-Vector-Ras | 2/6 | 3/9 | 0/9 | 0/9 |
| HMLE-Snail-Ras | 6/6 | 9/9 | 9/9 | 6/9 |
| HMLE-Twist-Ras | 6/6 | 9/9 | 9/9 | 7/9 |
