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Time protocol of acetone-induced skin barrier disruption
| Time (min) | TEWL (g/h/m2) |
|---|---|
| 0 | 9.4 |
| 3.5 | 9.8 |
| 5.5 | 13.5 |
| 7 | 25.9 |
| 9.5 | 47.3 |
| >11 | >60 |
The skin barrier is disrupted by means of acetone-soaked cotton swabs during various time periods. The barrier disruption is monitored by measuring the transepidermal water loss (TEWL)
