Table 1.

Summary of the included studies.

Study	Comparison	Design	Method	Mice	Genes identified
1	Paired supra and infrarenal aortas	Pooled samples	Codelink mouse whole genome bioarray (36227 genes)	10	Differentially expressed between AAA prone supra and infrarenal aorta
2	Whole aortas of mice exposed to angiotensin II that did and did not develop aneurysms and saline infused controls	Individual mice	Illumina mouse sentrix 6 microarray (46,628 genes).	18	Differentially expressed between the 3 groups revealing aneurysm-associated and "protective" genes
3	Suprarenal aortas of mice exposed to angiotensin II that did and did not develop aneurysms	Individual mice	ELISA and IHC	18*	Validate findings from the microarray in study 2 for Tnfrsf11b, Tgfb1, and inflammatory cell markers.

* 10 further mice died and were excluded from this study.