Table 8.

Comparison of results from this study and those from other expression arrays for AAA.

Ref.	Transcripts examined	Species	Number of samples/controls	Tissue of interest	Control tissue	Similar genes upregulated
9	18057 oligonucleotides microarray	Human	6/7	AAA	Normal#	Chemokines (e.g. CCL2, CCL4, CCL8, CCR5, CXCL5, CXCR4, TNFRSF13B) Pro-inflammatory cytokines (e.g. IL1B, IL2RG) Matrix metalloproteinase (e.g. MMP9) Cell lineage markers (e.g. CD53, CD68, CD72)
32‡	1181 cDNA clones	Mice	3/3**	Elastase induced AAA	Inactivated elastase infused aortas	Pro-inflammatory cytokines (e.g. IL1B, IL6, INF, IGF1) Chemokines (e.g. CCL7) JAK-STAT signalling (e.g. SOC3)
31‡	375 cDNA clones	Human	1/1*	AAA body	AAA neck	Chemokines (e.g. CXCR2)
28‡	265 cDNA clones	Human	7/5/5†	AAA	AOD and normal†	Matrix metalloproteinase (e.g. MMP9, MMP12) Pro-inflammatory cytokines (e.g. IL1B, IL6) Chemokines (e.g. CCL4, CCR5) Fibrinolysis (e.g. uPA)
33‡	8799 cDNA clones microarray	Rat	1/1‡‡	Elastase induced AAA	Saline infused aortas	Oxidative stress (Heme oxygenase, lipoxygenase)
34‡	1176 cDNA clones	Human	4/4	AAA	normal††	Cathepsins (e.g. cathepsin H) Matrix metalloproteinase (e.g. MMP9) Chemokines (e.g. CXCR4, CCL5)

*Results provided limited; †5 controls from aortic occlusive disease (AOD) from patients undergoing bypass and 5 controls from organ donors which were not age-matched; ‡These studies did not adjust for multiple testing; **pooling of samples was performed with 3 pools of interest compared with 3 controls for 4 different time periods after elastase infusion; ††Controls were from organ donor who were not matched; ‡‡Appears to have been comparison of one pool of samples from elastase induced aaas and one pool from controls examined on two microarrays each; #controls from post-mortem samples. Ref. = reference.