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. 2009 Sep;57(9):811–824. doi: 10.1369/jhc.2009.953307

Figure 1.

Figure 1

Endocrine cells clustering during human pancreas development. (A) Immunostaining of human fetal and adult pancreas with anti-insulin (green), anti-glucagon (red), and anti-Ki67 (blue) antibodies. Numbers in the image indicate the gestational age in weeks (wks). (B) Seventeen-week fetal pancreas immunostained with anti-insulin (green), anti-glucagon (red), and anti-somatostatin (blue) or pancreatic polypeptide (PP) (blue). INS, insulin; GCG, glucagon; SST, somatostatin. (C) Diameter measurement of islet-like clusters. Clusters ≥ 70 μm were counted, and the size values were plotted. The lines indicate the mean ± SEM of the average diameter of the clusters. Bar = 50 μm.