Table 3. Rate ratios for dose categories and estimated ERR (βˆ) for CBC in the < 45, 5+ subgroup using location and covariate effects estimated from all subjects (Global) and from the < 45, 5+ subgroup (Subgroup). CCML: Case-control-matched-location, CL: case-location, CCAL: case-control-all-location.
| Analysis method | Dose (Gy) | Number < 45, 5+ casesa | Global δˆ, γˆb RR (95% CI) | Subgroup δˆ, γˆc RR (95% CI) |
|---|---|---|---|---|
| CCML | 0 | 50 | 1 | 1 |
| .01-1 | 34 | 1.36 (0.79-2.34) | 1.34 (0.77-2.32) | |
| 1+ | 26 | 2.03 (1.08-3.79) | 2.03 (1.07-3.85) | |
| CLd | 0-.5 | 57 | 1 | 1 |
| .5-1 | 27 | 1.58 (0.50-5.01) | 1.74 (0.53-5.70) | |
| 1+ | 26 | 1.25 (0.37-4.22) | 2.10 (0.52-8.49) | |
| CCAL | 0 | 50 | 1 | 1 |
| .01-1 | 34 | 1.67 (1.01-2.78) | 1.46 (0.86-2.47) | |
| 1+ | 26 | 1.50 (0.86-2.61) | 1.78 (0.98-3.20) |
a
Dose at location of CBC.
b
Location (δ) and subject-level (γ) parameters were estimated from the full data set, 609 case-control sets.
c
All parameters estimated from the < 45, 5+ subgroup, 110 case-control sets.
d
Cannot use zero as baseline (see text).