Table 1.

Personal and disease characteristics of cases (N=4153) by Breast Cancer Family Registry

	All N=4153		Ontario N=1578		Northern California N=1306		Australia N=1269
	N	%	N	%	N	%	N	%
Age at diagnosis (years)
<35	542	13	135	9	191	15	216	17
35-39	578	14	146	9	74	6	358	28
40-44	558	13	224	14	167	13	167	13
45-49	776	19	348	22	241	19	187	15
50-54	784	19	371	24	229	18	184	15
55-59	474	11	135	9	182	14	157	12
≥60	441	11	219	14	222	17	0	0
Mean	47		43		49		48
Race/ethnicity
White	3133	76	1457	92	542	42	1134	89
Black	209	5	8	1	201	15	0	0
Hispanic	221	5	0	0	221	17	0	0
Asian	452	11	52	3	326	25	74	6
Other	79	2	47	3	16	1	16	1
Unknown	59	1	14	1	0	0	45	4
Number of affected lymph nodes
None	2242	54	823	52	740	57	679	54
1-3	976	23	377	24	286	22	313	25
≥4	495	12	163	10	159	12	173	14
Unknown	440	11	215	14	121	9	104	8
Mean	2		2		1		2
Tumor size (mm)
≤20	2579	62	941	60	786	60	852	67
>20	1303	31	505	32	440	34	358	28
Unknown	271	7	132	8	80	6	59	5
Mean	21		20		20		22
Tumor grade
1	788	19	312	20	291	22	185	15
2	1518	36	590	37	477	37	451	36
3	1522	37	554	35	407	31	561	44
Unknown	325	8	122	8	131	10	72	6
Histologic type
Ductal	3402	82	1372	87	1088	83	942	74
Lobular	245	6	102	7	53	4	90	7
Other	296	7	61	4	165	13	70	6
Unknown	210	5	43	3	0	0	167	13
Estrogen receptor status
Negative	1002	24	323	21	287	22	392	31
Positive	2717	65	1029	65	900	69	788	62
Unknown	434	11	226	14	119	9	89	7
Progesterone receptor status
Negative	1094	26	369	23	372	29	353	28
Positive	2602	63	968	61	808	62	826	65
Unknown	457	11	241	15	126	10	90	7
Chemotherapy
No	1404	34	583	37	461	35	360	28
Yes	2024	49	674	43	806	62	544	43
Unknown	725	18	321	20	39	3	365	29
Tamoxifen
No	1945	47	668	42	555	42	722	57
Yes	1623	39	576	37	742	57	305	24
Unknown	585	14	334	21	9	1	242	19
Family history of breast cancer*
None	2282	55	772	49	627	48	883	70
First-degree	1112	27	453	29	524	40	135	11
Second-degree	759	18	353	22	155	12	251	20

^*Based on self-report