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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Bioorg Med Chem Lett. 2009 Jul 10;19(17):5101–5104. doi: 10.1016/j.bmcl.2009.07.035

Table 2.

Reactivation rate constant (kr) for 8, 13, 20, 23 and 26

Entry kr [min−1]
EeAChE rHuAChE
2-PAM (1) 0.1766 ± 0.0134 0.0041 ± 0.0003
8 0.0406 ± 0.0021 0.0048 ± 0.0004
13 0.0108 ± 0.0002 0.0010 ± 0.0002
20 0.0339 ± 0.0026 0.0016 ± 0.0001
23 0.0189 ± 0.0004 0.0012 ± 0.0001
26 0.0138 ± 0.0008 0.0010 ± 0.0001