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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Dev Biol. 2009 Jul 1;333(1):161–172. doi: 10.1016/j.ydbio.2009.06.031

Table 1.

Quantification of results from migration, alcian blue and in situ hybridization analyses in cxcr4a morphant embryos.

Injection Cartilage Phenotype
Ethmoid
Plate
Reduced		 Hyposym-
pletic
Defects		 Ectopic
cxcr4a Morpholino
(MO)
(ng/nl)		 26/65
(40%)
cxcr4a MO (as
control for rescue)		 21/52
(40%)
cxcr4a/cxcr7b*
Morpholino
(ng/nl)		 37/64
(54%)
sdf1b Morpholino
(ng/nl)		 30/53
(56%)
cxcr4a mRNA
overexpression		 16/62
(26%)		 22/62
(35.5%)		 13/62
(21%)
cxcr4a
Morpholino+cxcr4a
mRNA(200pg)
rescue		 11/42
(26%)		 6/42
(14%)
*

cxcr7b morphants alone have no craniofacial phenotype