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Properties of hemoglobin based oxygen carriers
| Properties of Hemoglobin Based Oxygen Carriers
| |||
|---|---|---|---|
| Products
|
|||
| Characteristics | DCLHb (Baxter)15 | SFH-P (Northfield)21,23 | HBOC-201 (Biopure)26 |
| Solution Concentration (g/dL) | 10 | 10 | 12–14 |
| P50 (mmHg) | 32 | 20–22 | 40 |
| COP (mmHg) | 42 | 20–25 | 25 |
| Methemoglobin (%) | <5 | <5 | <10 |
| Average Weight (kDa) | 64 | 150 | 250 |
| Viscosity (cp) | 1.2 | 1.9–2.2 | 1.3 |
| In vivo Half-life (hrs) | 6–12 | 24 | 19 |
| Shelf-life (yrs) | 1+ | 1+ | 3 |
| Storage Temperature (°C) | <5 | 4–8 | 2–30 |
