Table 4.
Association of ADE from a medication discrepancy with 3 prescribing indices: number of medications prescribed prior to transfer, number of medication discrepancies that occurred after transfer, and number of high-risk medication discrepancies that occurred after transfer.
Index: | Pre-Transfer Medications | Medication Discrepancies | High-Risk Discrepancies | |||
---|---|---|---|---|---|---|
Quartile of index: | Range in quartile: | Percent in quartile with ADE: | Range in quartile: | Percent in quartile with ADE: | Range in quartile: | Percent in quartile with ADE: |
1 | 0–3 | 15 | 0 | 14 | 0 | 13 |
2 | 4–5 | 13 | 1 | 17 | 1 | 22 |
3 | 6–7 | 27 | 2–3 | 19 | 2 | 24 |
4 | ≥8 | 24 | ≥4 | 32 | ≥3 | 47 |
Unadjusted odds ratio (95% CI); C-statistic* | 1.08 (.98–1.19); .578 | 1.19 (1.05–1.36); .600 | 1.65 (1.26–2.16); .621 | |||
Adjusted** odds ratio (95% CI); C-statistic* | 1.07 (.97–1.19); .637 | 1.20 (1.02–1.41); .666 | 1.71 (1.28–2.28); .691 |
Odds ratio indicates the additional risk of ADE with a 1-point increase in each prescribing index; c-statistic indicates the area under the receiver operating characteristic (ROC) curve
Adjusted for gender, age, comorbidity score, APACHE score, off-hours admission, and duration of follow-up