FIG 3.
The effects of Relm-α on DSS-induced colitis. Wild-type (WT) and Retnla−/− mice were exposed to DSS for the indicated time points and analyzed for the clinical disease features diarrhea (A), rectal bleeding (B), and weight loss (C). The colon length of wild-type and Retnla−/− mice after DSS treatment was assessed (D). Mice were also monitored for survival after 3.5% DSS treatment (E). In Fig 3, A and B, the numbers in parentheses represent the actual number of mice that displayed clinical symptoms of disease development. Data are for a representative experiment of 4 (6-8 mice per experimental group). *P < .05, **P < .01, ***P < .001. Ctrl, Control.