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The increase in particular protein domains during adhesome evolution
| Protein domain | Number of proteins with the domain at each evolutionary stage | |||
| Integrin-independent | Protostome | Deuterostome | Tetrapod | |
| SH3 | 5 | 27 | 33 | 34 |
| PH | 5 | 16 | 21 | 23 |
| SH2 | 3 | 15 | 20 | 22 |
| CH | 2 | 7 | 9 | 10 |
| LIM | 1 | 4 | 6 | 10 |
| FERM | 1 | 7 | 9 | 9 |
| ANK | 2 | 4 | 5 | 5 |
| PDZ | 0 | 2 | 3 | 3 |
| SPEC | 2 | 4 | 4 | 4 |
