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. Author manuscript; available in PMC: 2009 Aug 18.
Published in final edited form as: Circ Res. 2008 Jun 6;102(11):1319–1330. doi: 10.1161/CIRCRESAHA.108.175943

Figure 2. Cell enhancement strategy.

Figure 2

Stem/progenitor cells isolated from various sources can be pre-activated or modified to enhance incorporation and functional activity before being infused or injected in patients with acute or chronic heart disease. The optimal chose of the pre-treatment likely depends on the cell type and the mode of delivery. While cell survival appears a major limitation for intramyocardial delivery, homing functions are essential if cells are infused via the coronary arteries.