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Histopathology of C57/BL6 mice three days post i.p. injection of 7mg/kg cisplatin
| BL6 1 | BL6 2 | BL6 3 | |
|---|---|---|---|
| Liver | |||
| - hepatic necrosis | 0 | 0 | 0 |
| - centrilobular fatty change | 3 | 3 | 2 |
| - inflammation | 0 | 0 | 0 |
| Colon | |||
| - crypt necrosis/apoptosis | 1 | 1 | 1 |
| Kidney | |||
| - tubular nephrosis/apoptosis | 4 | 4 | 3 |
| - tubular vacuolation/degeneration | 3 | 3 | 2 |
| - tubular mineralization | 2 | 0 | 2 |
| - inflammation | 0 | 0 | 0 |
0= absent or no significant lesions
1= minimal lesions
2= mild lesions
3= moderate lesions
4= marked lesions
