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. Author manuscript; available in PMC: 2010 Jun 1.

Published in final edited form as: J Neuropathol Exp Neurol. 2009 Jun;68(6):626–632. doi: 10.1097/NEN.0b013e3181a491ce

HoxA5 reduces HIF1α in BH. A) Photomicrographs show HIF-1α (red), CD31 (green) and dapi (blue) expression within the hemangioma-like lesion in the EOMA (a, b), or HoxA5-expressing EOMA cells (c, d) transplanted into the mouse brain after 2 weeks of injection. Arrows point to representative positive nuclei staining for HIF-1α. Scale bar (a, c) = 40 μm, (b, d) =10 μm. B) Bar graph shows the average number of HIF-1α positive cells counted per field per group at each time point. Data are mean±SD, n=6 in each group. *, p<0.05 for the difference between EOMA+HoxA5 vs. EOMA group for same time point.

HoxA5 reduces HIF1α in BH. A) Photomicrographs show HIF-1α (red), CD31 (green) and dapi (blue) expression within the hemangioma-like lesion in the EOMA (a, b), or HoxA5-expressing EOMA cells (c, d) transplanted into the mouse brain after 2 weeks of injection. Arrows point to representative positive nuclei staining for HIF-1α. Scale bar (a, c) = 40 μm, (b, d) =10 μm. B) Bar graph shows the average number of HIF-1α positive cells counted per field per group at each time point. Data are mean±SD, n=6 in each group. *, p<0.05 for the difference between EOMA+HoxA5 vs. EOMA group for same time point.