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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Pancreas. 2008 Oct;37(3):e39–e44. doi: 10.1097/MPA.0b013e318176b9ae

Table 1.

Summary of ductal-islet interface abnormalities in Pdx-1-Aurora A transgenic mice

Mouse # Line Ductal-Islet Interface Comments Other Tissue Effects
dysplasia normal total
3 A 2 2 2/4 much lipoatrophy, many islets
4 A 1 2 1/3 fairly normal parenchyma focal lymphocytic infiltration & mild fibrosis
5 A 3 0 3/3 moderate ductal dysplasia*
6 A 0 1 0/1 fairly normal parenchyma mild acinar hypertrophy/dysplasia
7 A 3 0 3/3 mild ductal dysplasia
8 A 2 2 2/4 mild ductal dysplasia focal lymphocytic infiltration; fibrotic lesion
TOTAL A 11 7 11/18
9 B 0 2 0/2 fairly normal parenchyma odd ductal lesion; focal lymphocytic infiltration
TOTAL B 0 2 0/2
TOTALS A & B 11 9 11/20
Controls N/A 0 12 0/12 normal parenchyma
*

most other ductal dysplasia was mild