TABLE 4.
Relative risks (RRs) and 95% CIs of incident hypertension in 31,684 men by quintile of total germ intake: Health Professionals Follow-Up Study, 1986–20041
Quintile of germ intake |
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1 | 2 | 3 | 4 | 5 | P for trend | |
Median intake (g/d)2 | 0.1 (0–0.2) | 0.4 (0.3–0.5) | 0.7 (0.6–0.8) | 1.1 (0.9–1.5) | 2.4 (1.6–58.6) | — |
No. of cases | 1772 | 1965 | 1875 | 1912 | 1703 | — |
Person-years | 60,986 | 71,150 | 68,236 | 74,442 | 70,546 | — |
Age- and energy-adjusted RR3 | 1.00 | 0.93 (0.87, 1.00) | 0.89 (0.83, 0.95) | 0.84 (0.79, 0.90) | 0.78 (0.73, 0.84) | <0.0001 |
Multivariate-adjusted RR3,4 | 1.00 | 1.02 (0.95, 1.09) | 1.02 (0.93, 1.08) | 1.00 (0.93, 1.08) | 0.96 (0.88, 1.04) | 0.11 |
RRs derived from proportional hazards models.
Ranges in parentheses.
95% CIs in parentheses.
Adjusted for age, energy, family history of coronary heart disease, family history of hypertension, smoking, alcohol, marital status, profession, height, fruit and vegetable intakes, sodium intake, physical activity, multivitamin use, and cholesterol screening.