Fig. 11.

Time course release of the dual labeled biodegradable nanocarrier in 10 μM GSH at 37 °C: The heterodimeric nanocarrier was dissolved in 100 mM PB pH 7.4±0.2 in presence of 10 μM reduced GSH. At each time point (0,15,30,60 and 90 minutes), 1% TFA was added to the sample to stop the reduction reaction by GSH. The zero time point is identical to other sample with the exception that it did not contain any GSH. All experiments were performed in triplicate.