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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Exp Neurol. 2009 Jun 11;219(1):334–340. doi: 10.1016/j.expneurol.2009.06.005

Table 1.

Stereological estimates of the total number of Nissl-stained, TH-immunoreactive neurons in the SNc and reference volumes (Cavalieri method) of the region.

Animal treatment N Mean Vr ± SEM (mm3)
Total Number of SNc Neurons ± SEM CE
MPTP/probenecid 8 0.164 ± 0.003 3112 ± 100*§ 0.11
probenecid 6 0.170 ± 0.004 9745 ± 254 0.09
saline 6 0.178 ± 0.008 9836 ± 100 0.08

Vr: reference volume; CE: coefficient of error for neuron estimates

*

significantly fewer neurons in SNc after MPTP/probenecid treatment compared to probenecid or saline

(Kruskal-Wallis test,* P < 0.001; Dunnets post hoc test, §P < 0.001 compared to probenecid control and §P < 0.001 compared to saline control).