Table 2.
Participant Characteristics at Year 20 by FABP2 genotype, The CARDIA Study, 2005–2006
| AA/AG (n=1145) | GG (n=1552) | P-value | |
|---|---|---|---|
| Race | |||
| Black | 522 (45.6) | 738 (47.6) | 0.32 |
| White | 623 (54.4) | 814 (52.5) | |
| Sex | |||
| Male | 465 (40.6) | 680 (59.4) | 0.24 |
| Female | 665 (42.8) | 887 (57.2) | |
| Age | 45.2 ± 0.1 | 45.0 ± 0.1 | 0.32 |
| Center | |||
| Birmingham | 270 (23.6) | 338 (21.8) | 0.62 |
| Chicago | 268 (23.4) | 355 (22.9) | |
| Minneapolis | 300 (26.2) | 418 (26.9) | |
| Oakland | 307 (26.8) | 441 (28.4) | |
| Education | |||
| ≤ High School | 222 (20.9) | 298 (20.5) | 0.01 |
| Some College | 289 (27.2) | 468 (32.3) | |
| College | 286 (27.0) | 390 (26.9) | |
| Graduate School | 264 (24.9) | 295 (20.3) | |
| BMI, kg/m2 | |||
| <25 | 327 (28.6) | 489 (31.7) | 0.23 |
| 25 to <30 | 389 (34.1) | 504 (32.7) | |
| ≥ 30 | 426 (37.3) | 548 (35.6) | |
| Waist, cm | 91.1 ± 0.5 | 90.8 ± 0.4 | 0.66 |
| Smoking Status | |||
| Never | 703 (62.1) | 963 (62.6) | 0.39 |
| Former | 228 (20.1) | 281 (18.3) | |
| Current | 201 (17.8) | 294 (19.1) | |
| Alcohol, ml/day | 10.4 ± 0.6 | 11.0 ± 0.6 | 0.46 |
| Physical Activity, EU | 339.9 ± 8.3 | 345.0 ± 7.1 | 0.64 |
| Saturated Fat, g/day | 31.3 ± 0.6 | 31.1 ± 0.5 | 0.83 |
| Energy Intake, kcal/day | 2415.7 ± 41.0 | 2389.0 ± 35.1 | 0.62 |
| Total Cholesterol, mg/dL | 186.7 ± 1.0 | 185.4 ± 0.9 | 0.32 |
| LDL Cholesterol, mg/dL | 111.1 ± 0.9 | 110.2 ± 0.8 | 0.49 |
| HDL Cholesterol, mg/dL | 55.3 ± 0.5 | 54.6 ± 0.4 | 0.33 |
| Triglycerides, mg/dL | 101.8 ± 1.8 | 102.7 ± 1.5 | 0.73 |
| HDL/TC ratio | 0.3 ± 0.003 | 0.3 ± 0.003 | 0.74 |
| Diabetes | |||
| No | 1061 (93.8) | 1464 (94.8) | 0.29 |
| Yes | 70 (6.2) | 81 (5.2) | |
| HOMA-IR | 4.0 ± 0.1 | 3.9 ± 0.1 | 0.46 |
Values are N (%) for categorical variables, and mean ± SEM for continuous variables