A–E: Box plots of 5 components of the neurobehaviuoral testing Posture, righting reflex, Locomotion score, muscle tone and dystonia. Normal control animals score 3 on posture, righting reflex and locomotion and 1 on muscle tone and dystonia. The JI-8 treated animals are closer to controls than the saline treated animals. F. On the swim test, the angular velocity decreased after the Dam was treated with a potent nNOS inhibitor, JI-8. The x axis shows the joint and treatment with P1 kits in white and P5 in hatched bars. The Y axis shows maximum angular velocity of the joint.