Table 1.
Data From All Available Studies on Deletions in Neurexin 1
| All Deletions >100 kb | Deletions >100 kb Disrupting Exons | ||||
| Study | Cases | Controls | Size (kb) | Cases | Controls |
| Kirov et al14 | 1/93 | 0/372 | 250 | 1/93 | 0/372 |
| Walsh et al15 | 1/233 | 0/268 | 115 | 1/233 | 0/268 |
| International Schizophrenia Consortium17 | 4/3391 | 3/3181 | 122–291 | 3/3391 | 1/3181 |
| Rujescu et al16 | 6/2977 | 11/33 746 | 100–419 | 5/2977 | 5/33 746 |
| Need et al18 | 3/1073 | 0/1148 | 200–418 | 3/1073 | 0/1148 |
| Kirov et al19 | 1/471 | 3/2792 | 231–631 | 1/471 | 3/2792 |
| Ikeda et al. (unpublished data, 2009, see text citation for all authors) | 1/560 | 0/547 | 161 | 0/560 | 0/547 |
| Totals | 17/8798 (0.19%) | 17/42054 (0.04%)a | 14/8798 (0.16%) | 9/42 054 (0.02%)b | |
Note: All deletions are filtered for >100kb in size
a
Fisher Exact test: P = .000013, odds ratio = 4.78, 95% confidence interval = 2.44–9.37.
b
Fisher Exact test: P = .0000037, odds ratio = 7.44, 95% confidence interval = 3.22–17.18.