Table 2. Outcome of twins at 2 years of age in relation to chorionicity.
| Parameter | MC twins | DC twins | P value | Mean difference (95% CI) | Adjusted mean difference (95% CI)‡ |
| No. of long-term survivors | 140 | 142 | |||
| Age at testing | |||||
| Chronological age | 23+7 months | 23+2 months | 0.178 | ||
| Corrected age | 22+3 months | 22+2 months | 0.326 | ||
| Physical exam | |||||
| Height (cm), mean (SD) | 86.0±3.4 | 86.5±3.7 | 0.239 | ||
| Weight (kg), mean (SD) | 12.3±1.4 | 12.2±1.3 | 0.831 | ||
| Head circumference (cm), mean (SD) | 48.6±1.6 | 48.6±1.4 | 0.978 | ||
| Home environment | |||||
| Older siblings | 72 (49.0) | 53 (37.3) | 0.057 | ||
| multilingual education | 17 (11.6) | 9 (6.3) | 0.151 | ||
| Griffiths Test | |||||
| Total score 1 | |||||
| mean DQ (SD) | 103±9 | 104±11 | 0.423 | −0.96 (−3.33; 1.40) | 0.34 (−1.88; 2.55) |
| Mild developmental delay | 1 (0.7) | 4 (2.8) | 0.370 | ||
| Severe developmental delay | 0 | 2 (1.4) | 0.498 | ||
| Subscale A; locomotor | |||||
| mean DQ (SD) | 93±10 | 94±13 | 0.493 | −0.96 (−3.70; 1.78) | −0.48 (−3.26; 2.31) |
| Mild developmental delay | 36 (26.5) | 38 (26.8) | 0.893 | ||
| Severe developmental delay | 0 | 5 (3.5) | 0.060 | ||
| Subscale B; personal-social | |||||
| mean DQ (SD) | 103±10 | 102±12 | 0.593 | 0.69 (−1.87; 3.25) | 1.93 (−0.54; 4.40) |
| Mild developmental delay | 6 (4.8) | 6 (4.2) | 1.000 | ||
| Severe developmental delay | 0 | 3 (2.1) | 0.247 | ||
| Subscale C; hearing & language | |||||
| mean DQ (SD) | 99±14 | 102±14 | 0.084 | −2.82 (−6.01; 0.38) | −0.72 (−3.66; 2.23) |
| Mild developmental delay | 19 (13.8) | 8 (5.6) | 0.026 | ||
| Severe developmental delay | 1 (0.7) | 5 (3.5) | 0.214 | ||
| Subscale D; eye-hand coordination | |||||
| mean DQ (SD) | 107±9 | 106±12 | 0.264 | 1.46 (−1.11; 4.03) | 2.35 (−0.18; 4.88) |
| Mild developmental delay | 1 (0.7) | 4 (2.8) | 0.371 | ||
| Severe developmental delay | 0 | 2 (1.4) | 0.492 | ||
| Subscale E; performance | |||||
| mean DQ (SD) | 109±14 | 111±15 | 0.372 | −1.56 (−5.00; 1.88) | −0.55 (−4.00; 2.90) |
| Mild developmental delay | 5 (4.3) | 5 (3.6) | 1.000 | ||
| Severe developmental delay | 3 (2.1) | 2 (1.5) | 0.683 | ||
Notes:
1
In 10 cases incomplete testing (5 MC and 5 DC infants).
DQ = developmental quotient.
‡
Adjusted for gender, older sibling in family and multilingualism.