Figure 2.—

Performance of single-locus and multilocus methods in mapping two QTL in 1000 simulated F₁₈ advanced intercrosses. (A) Plot of predictions at a range of cutoffs for the maximum log P in a segment (single-locus model and hard, soft, and pedigree correction, mixed model) or the range probability over a segment (subagging with 80% subsamples, bagging). Forward selection is a discrete classifier, has no applicable threshold, and so is represented as a single point. (B) Plot of the area under the curves in plot (A), including results for variants of subagging in which the proportion of data subsampled varies (40–90%) and the stopping rule used in forward selection is made stricter (see simulations for details). Area estimates, calculated via the trapezium rule over a grid of values, are plotted with 50 and 95% confidence intervals (thick and thin horizontal bars).