Table 3.

Allergic outcomes measured over the 12-week study period

	Hookworm mean (SD) (n=13)	Placebo mean (SD) (n=14)	Mean difference (95% CI)	P-value	Adjusted* mean difference (95% CI)	P-value
Juniper RQLQ score (log AUC)	6.01 (0.82)	5.68 (0.85)	0.33 (−0.33, 1.00)	0.31	0.26 (−0.45, 0.97)	0.46
Change in grass SPT reaction (mm)	0.73 (2.65)	0.11 (2.65)	0.62 (−1.48, 2.73)	0.55	1.18 (−0.94, 3.30)	0.26
Change in cat fur SPT reaction (mm)	−0.27 (2.09)	−0.75 (1.83)	0.48 (−1.07, 2.03)	0.53	0.64 (−1.01, 2.29)	0.43
Change in DP SPT reaction (mm)	1.27 (2.19)	0.54 (2.59)	0.74 (−1.18, 2.64)	0.44	0.85 (−1.19, 2.90)	0.40

^*All adjusted for smoking status; Juniper RQLQ additionally adjusted for baseline score.

95% CI, 95% confidence interval; DP, Dermatophagoides pteronyssinus.