Table 1.
Myocardial Infarct Phenotype before and 12 weeks after treatment
Parameter | Groups | Week 12 | Week 24 | P |
---|---|---|---|---|
MI Size, %LV mass | Placebo | 19.6 ± 1.5 | 20.6 ± 1.1 | 0.76 |
MSC | 19.3 ± 1.7 | 13.9 ± 2.0 | <0.001*† | |
Infarct volume, mL | Placebo | 7.1 ± 0.4 | 8.0 ± 0.4 | 0.06 |
MSC | 7.4 ± 1.2 | 5.4 ± 1.1 | <0.001† | |
LV mass, g | Placebo | 36.5 ± 1.9 | 39.0 ± 0.6 | 0.75 |
MSC | 37.1 ± 3.2 | 37.5 ± 2.6 | 0.58 | |
Circumferential extent of MI, % LV | Placebo | 40.1 ± 2.8 | 40.3 ± 2.8 | 0.73 |
MSC | 42.1 ± 2.1 | 28.0 ± 2.8 | <0.001*† | |
Wall thickness infarct, mm | Placebo | 4.0 ± 0.1 | 3.6 ± 0.2 | 0.12 |
MSC | 3.9 ± 0.2 | 4.9 ± 0.4 | 0.049*† | |
Wall thickness remote, mm | Placebo | 7.1 ± 0.5 | 7.4 ± 0.5 | 0.69 |
MSC | 6.6 ± 0.5 | 6.9 ± 0.3 | 0.62 |
*ANOVA between groups.
†ANOVA within groups.