Table 1.
Published Functional Imaging Studies in PTSD-Methods
| Authors | Study Population | Sample Size | Control Group | Sample Size | Imaging Methods | Active Condition | Control |
|---|---|---|---|---|---|---|---|
| Rauch 96 | Mixed PTSD | 8 | none | 0 | PET O-15 | Combat scripts | neutral scripts |
| Semple 96 | Combat PTSD+SA | 6 | Healthy subjects | 6 | PET FDG | Continuous Performance T | Rest |
| Bremner 97 | Combat-related PTSD | 10 | Healthy subjects | 10 | PET FDG | Yohimbine | Placebo |
| Shin 97 | Combat-related PTSD | 7 | Combat veterans without PTSD | 7 | PET O-15 | Trauma Imagery/Perceptio | Neg/Neutral Image/Percep |
| Bremner 99a | Combat-related PTSD | 10 | Combat veterans without PTSD | 10 | PET O-15 | Combat slides/sounds | Neutral slides/sounds |
| Bremner 99b | Women with Abuse-related PTSD | 10 | Abused Women without PTSD | 12 | PET O-15 | Abuse scripts | neutral scripts |
| Shin 99 | Women with Abuse-related PTSD | 8 | Abused Women without PTSD | 8 | PET O-15 | Abuse scripts | neutral scripts |
| Liberzon 99 | Combat-related PTSD | 14 | Healthy subjects/combat controls | 14/11 | SPECT HMP | Combat Sounds | White Noise |
| Zubieta 99 | Combat-related PTSD | 12 | Combat veterans without PTSD, Healthy Subj | 11/12 | SPECT HMP | Combat Sounds | White Noise |
| Rauch 00 | Combat-related PTSD | 8 | Combat veterans without PTSD | 8 | fMRI | Masked Fearful Faces | Masked Happy Faces |
| Semple 00 | Combat PTSD+SA | 6 | Healthy subjects | 7 | PET O-15 bu | Continuous Performance T | Rest |
| Shin 01 | Combat-related PTSD | 8 | Combat veterans without PTSD | 8 | fMRI | Counting Stroop-combat | Stroop General Negative |
| Lanius 01 | Mixed Civilian (SA or MVA) | 9 | Traumatized non-PTSD | 9 | fMRI | Traumatic Scripts | Resting state |
| Pissiota 02 | Combat PTSD | 7 | none | 0 | PET | Traumatic sounds | neutral sounds |
| Lanius 03 | Mixed Civilian (SA or MVA) | 10 | Traumatized non-PTSD | 10 | fMRI | sad, anxious, trauma scrip | Resting state |
| Bremner 03 | Women with Abuse-related PTSD | 10 | Healthy Women | 11 | PET O-15 | Trauma related word recal | shallow encoding |
| Bremner 03b | Women with Abuse-related PTSD | 10 | Women with abuse without PTSD | 12 | PET O-15 | Memory task | shallow encoding |
| Clark 03 | Civilian PTSD | 10 | Healthy subjects | 10 | PET O-15 | Working memory task | Fixed target |
| Bonne 03 | Civilian PTSD | 11 | trauma controls/healthy controls | 17/11 | SPECT HMP | Resting state | |
| Bremner 05 | Women with Abuse-related PTSD | 8 | Healthy subjects | 11 | PET O-15 | Fear conditioning | Unpaired CS-US |
| Bremner 04 | Women with Abuse-related PTSD | 12 | Women with abuse without PTSD | 9 | PET O-15 | Emotional Stroop | Neutral Stroop |
| Shin 04 | Vietnam Combat related PTSD | 17 | Vietnam veterans without PTSD | 19 | PET O-15 | Traumatic Scripts | neutral scripts |
| Shin 04b | Firefighters with PTSD | 8 | Firefighters without PTSD | 8 | PET O-15 | Memory task | shallow encoding |
| Lindauer 04 | Policemen with PTSD | 15 | Policemen without PTSD | 15 | SPECT HMP | Traumatic Scripts | neutral scripts |
| Yang 04 | Children - Earthquake related PTS | 5 | Children - Earthquake - nonPTSD | 6 | fMRI | Earthquake pictures/image | Neutral pictures/imagery |
| Shin 05 | Firefighters+VN Combat with PTS | 13 | Trauma exposed without PTSD | 13 | fMRI | Overt fearful faces | neutral overt faces |
| Armony 05 | Acute PTSD - MVA | 13 | None | 0 | fMRI | Masked Fearful Faces | Masked Happy Faces |
| Sakamoto 05 | Mixed civilian PTSD | 16 | Healthy subjects | 16 | fMRI | Masked traumatic images | masked neutral images |
| Protopopescu 05 | Sexual/physical abuse PTSD | 11 | Healthy subjects | 21 | fMRI | Traumatic word recall | neutral word recall |
| Bryant 05 | Civilian PTSD | 14 | Healthy Controls | 14 | fMRI | Oddball Working Memory | |
| Britton 05 | Combat PTSD | 16 | Combat controls/Healthy controls | 15/14 | PET O-15 | traumatic scripts | neutral scripts |
| Chung 06 | Civilian PTSD | 23 | Healthy Controls | 46 | SPECT HMP | Resting state | None |
| Phan 06 | Vietnam Combat related PTSD | 16 | Combat controls/healthy subjects | 15/15 | PET | Negative pictures | control pictures |
| Astur 06 | Civilian PTSD | 12 | Healthy Controls | 12 | fMRI | virtual water maze | visual condition |