Table 2.
Ultrastructural change | ||||
---|---|---|---|---|
Mean difference in score, ApoB100 vs. wild type* | P value | Mean difference in score, High fat diet vs. normal diet** | P value | |
RPE infolding | 1.0 | <0.001 | 0.01 | 0.96 |
RPE vacuoles |
0.2 for high fat diet 1.6 for normal diet |
<0.001 <0.001 |
0.3 for aboB100 1.1 for wild type |
0.96 <0.001 |
BlamD | 0.7 | 0.033 | 0.06 | 0.93 |
BlamD, Continuity | 0.6 | 0.012 | 0.2 | 0.46 |
BlamD, content | 0.5 | 0.04 | 0.02 | 0.94 |
OCL | 1.6 | <0.001 | 0.35 | 0.07 |
OCL, Continuity | 0.8 | 0.001 | 0.04 | 0.78 |
OCL, Content | 0.5 | 0.019 | 0.04 | 0.76 |
CC basement membrane | 0.6 | 0.002 | 0.12 | 0.53 |
CC, loss of fenestrations | 0.4 | 0.010 | 0.01 | 0.91 |