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. Author manuscript; available in PMC: 2009 Aug 19.
Published in final edited form as: Nat Genet. 2009 Jan 18;41(2):178–186. doi: 10.1038/ng.298

Figure 4.

Figure 4

Gene expression is strongly correlated with T-DMRs at CpG island shores. For each brain versus liver T-DMR we found the closest annotated gene on the Affymetrix HGU133A microarray, resulting in a total of 2,041 gene/T-DMR pairs. Plotted are log (base 2) ratios of liver to brain expression against delta M values for liver and brain DNAm. Orange dots represent T-DMRs located within 300 bp from the corresponding gene's transcriptional start site (TSS). Green dots represent T-DMRs that are located from 300-2000 bp from the TSS of an annotated gene. Black dots, in the middle, represent log ratios for all genes further than 2 kb from an annotated TSS.