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. Author manuscript; available in PMC: 2010 Apr 18.
Published in final edited form as: Tetrahedron. 2009 Apr 18;65(16):3211–3221. doi: 10.1016/j.tet.2008.10.107

Table 3.

Substrate scope of Pd-catalyzed enyne cyclization reactionsa.

Entry Substrate Product Yieldb
1 graphic file with name nihms120628t9.jpg graphic file with name nihms120628t10.jpg 79%
2 graphic file with name nihms120628t11.jpg graphic file with name nihms120628t12.jpg 55%
3 graphic file with name nihms120628t13.jpg graphic file with name nihms120628t14.jpg 78%
4 graphic file with name nihms120628t15.jpg graphic file with name nihms120628t16.jpg 66%
5 graphic file with name nihms120628t17.jpg graphic file with name nihms120628t18.jpg 70%
6 graphic file with name nihms120628t19.jpg graphic file with name nihms120628t20.jpg 55%
7 graphic file with name nihms120628t21.jpg graphic file with name nihms120628t22.jpg 48%
8 graphic file with name nihms120628t23.jpg graphic file with name nihms120628t24.jpg 41%
9 graphic file with name nihms120628t25.jpg graphic file with name nihms120628t26.jpg 44%
10 graphic file with name nihms120628t27.jpg graphic file with name nihms120628t28.jpg 71%
11 graphic file with name nihms120628t29.jpg graphic file with name nihms120628t30.jpg 47%
a

Reaction Conditions: 5 mol % Pd(OAc)2, 0-6 mol % bipy, 1.1-4 equiv PhI(OAc)2, 60-80 °C, 1-16 h.

b

Isolated yields (average of two runs).