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. 2008 Jan 29;93(4):1224–1230. doi: 10.1210/jc.2006-2300

Table 1.

TSH distribution using the ELISA for the entire cohort and by NRG

TSH (μIU/ml)
n Mean sd Median Minimuma Maximum 2.5th percentileb 97.5th percentileb
All 1861 1.81 2.78 1.35 <0.04 88.7 0.25 5.67
 Males 895 1.58 1.67 1.22 <0.04 26.3 0.44 4.40
 Females 966 2.01 3.49 1.47 <0.04 88.7 0.06 6.50
NRG-1c 1448 1.54 0.82 1.35 0.32 4.98 0.52 3.73
 Males 779 1.43 0.78 1.22 0.33 4.80 0.50 3.73
 Females 669 1.67 0.84 1.49 0.32 4.98 0.54 3.76
NRG-2c 1186 1.45 0.73 1.30 0.32 4.79 0.53 3.37
 Males 673 1.39 0.73 1.21 0.36 4.79 0.52 3.38
 Females 513 1.53 0.72 1.40 0.32 4.05 0.53 3.37
NRG-3c 766 1.48 0.74 1.32 0.36 4.79 0.54 3.37
 Males 480 1.41 0.73 1.24 0.36 4.79 0.54 3.28
 Females 286 1.61 0.75 1.47 0.38 4.05 0.55 3.37
a

There were 18 female subjects and one male subject with TSH by ELISA less than 0.04. 

b

Percentiles were estimated nonparametrically, not from fitted Gaussian or lognormal distributions. 

c

NRG-1 excludes those with thyroid disease, on thyroid hormone, and on medications that may affect thyroid function (lithium, amiodarone, glucocorticoids, Dilantin, Tegretol). NRG-2 additionally excludes those with positive antithyroid peroxidase or positive antithyroglobulin, and NRG-3 additionally excludes those with thyroid ultrasound abnormalities. 

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