Table 2.
Characteristics of participants in the WBF and UDCA trials combined, by category of body mass index.
| Category of Body Mass Index1 | ||||
|---|---|---|---|---|
| Characteristics | Normal Weight | Overweight | Obese | |
| n=739 | n=1120 | n=606 | ||
| Age at baseline (mean ± sd) | 67.0 ± 9.0 | 66.5 ± 8.4 | 63.8 ± 8.423 | |
| Male, n (%) | 418 (56.6) | 834 (74.5)2 | 411 (67.8)23 | |
| White, n (%) | 705 (96.1) | 1059 (95.2) | 566 (94.7) | |
| Family History CRC, n (%)4 | 151 (20.4) | 259 (23.3) | 132 (21.8) | |
| Current Smoker (yes), n (%) | 131 (18.1) | 118 (10.6)2 | 60 (10.1)2 | |
| Number of colonscopies(mean ± sd) | 1.8± 0.9 | 1.8 ± 0.8 | 1.8 ± 0.9 | |
| Previous Polyps (yes), n (%)5 | 279 (41.0) | 458 (45.0) | 231 (41.8) | |
| Aspirin Use (yes), n (%)6 | 206 (27.9) | 316 (28.2) | 170 (28.1) | |
| Baseline Adenoma Characteristics | ||||
| Number > 1 (yes), n (%) | 272 (36.9) | 482 (43.0)2 | 256 (42.2)2 | |
| Large, n (%) | 323 (43.9) | 487 (44.0) | 258 (42.7) | |
| Villous histology, n (%) | 154 (21.0) | 215 (19.4) | 146 (24.2) | |
| Proximal Location, n (%) | 215 (29.3) | 343 (31.0) | 186 (30.8) | |
| Adenoma Recurrence Rates, n (%) | ||||
| Non-advanced adenoma (Total Population) | 211 (28.6) | 344 (30.7) | 202 (33.3)2 | |
| Men7 | 134 (32.1) | 263 (31.5) | 149 (36.3) | |
| Women8 | 77 (24.0) | 81 (28.3) | 53 (27.2) | |
| Advanced adenoma9 (Total Population) | 105 (14.2) | 187 (16.7)2 | 85 (14.0) | |
| Men | 53 (12.7) | 153 (18.3)2 | 64 (15.6) | |
| Women | 52 (16.2) | 34 (11.9) | 21 (10.8) | |
Normal weight is a BMI of greater than 18.5 and less than 25; Overweight is a BMI of greater than or equal to 25 and less than 30; Obese is a BMI of greater than or equal to 30.
Value significantly different from normal weight, p <0.05.
Value significantly different from overweight, p <0.05.
Family history of colorectal cancer in one or more first degree relatives.
History of polyps prior to baseline.
Aspirin use in the last month at baseline.
The number of men in each category was 418 for normal weight, 834 for overweight, and 411 for obese.
The number of women in each category was 321 for normal weight, 286 for overweight, and 195 for obese.
Adenomas were classified as advanced if they had a diameter of 1 cm or more and/or tubulovillous or villous histology (at least 25% villous).