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. Author manuscript; available in PMC: 2010 Jul 2.
Published in final edited form as: Circ Res. 2009 May 28;105(1):89–98. doi: 10.1161/CIRCRESAHA.109.197145

Figure 3.

Figure 3

Clic4-/- mice have fewer hindlimb collaterals. X-ray arteriogram (a) and averaged data (b) showing arterial vessels crossing the collateral zone (dotted line) of the posterior thigh after acute ligation (native collaterals) and 7 days after ligation (remodeled collaterals). c) Lectin staining for capillaries in non-ischemic (baseline) WT gastrocnemius muscle. d) Clic4-/- tended toward greater atrophy measured at day-10 after ligation. e) Capillary-to-muscle fiber number ratio tended toward less increase in Clic4-/-. Values within bars are percentage change from non-ligated limb (baseline). *,**,*** p<0.05, 0.01 vs. white bar or as bracketed; n=4 per bar (panel b) and n=10 (panels d,e).