Figure 5.
Collateral remodeling and angiogenesis are attenuated in VEGFlo/+ mice. Capillary number-to-muscle fiber number ratios (a,b) and collateral lumen diameters (c,d) at baseline and day-21 post-ligation. Paired t-Test vs. Baseline; Unpaired t-test vs. wild-type; #p<0.05 vs. percentage change from wild-type; n=7-11 per data-point. (e) Immunofluorescent localization of VEGF in VEGFhi/+ mice. Non-collateral arteriole (left panel) and gracilis collateral at day-0 (middle panel) and day-7 post-ligation (right panel).
