Table 3.
Beta-coefficients and 95% CI for the association between maximal common cIMT, internal cIMT and sex hormone levels
Common Carotid Intimal-Medial Thickness (Units of beta are log-unit thicker IMT/per 1 log unit greater sex hormone level) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Model 1 (adjusted for age and ethnicity) N=1947 | Model 2 (Model 1 and adjustment for BMI) N=1947 | Model 3 (Model 2 and adjustment for hypertension, diabetes, smoking, QUICKI, excluding insulin use) N=1871 | |||||||
β -coeff | 95% CI | p-value | P-coeff | 95% CI | p-value | β -coeff | 95% CI | p-value | |
| |||||||||
Ln Testosterone | 0.021 | 0.008 to 0.034 | 0.001 | 0.018 | 0.005 to 0.037 | 0.006 | 0.018 | 0.005 to 0.031 | 0.009 |
Ln Bioavailable Testosterone | 0.027 | 0.015 to 0.038 | <0.001 | 0.022 | 0.013 to 0.034 | <0.001 | 0.019 | 0.007 to 0.032 | 0.002 |
Ln Estradiol | 0.005 | -0.008 to 0.018 | 0.446 | -0.001 | -0.14 to 0.012 | 0.848 | -0.006 | -0.019 to 0.007 | 0.389 |
Ln DHEA | 0.003 | -0.014 to 0.019 | 0.761 | 0.001 | -0.15 to 0.017 | 0.913 | -0.007 | -0.024 to 0.010 | 0.398 |
Ln SHBG | -0.030 | -0.048 to -0.12 | 0.001 | -0.021 | -0.040 to -0.003 | 0.026 | -0.010 | -0.030 to 0.011 | 0.342 |
| |||||||||
Internal Carotid Intimal-Medial Thickness (Units of beta are log-unit thicker IMT/per 1 log unit greater sex hormone level) | |||||||||
| |||||||||
Model 1 (adjusted for age and ethnicity) N=1914 | Model 2 (Model 1 and adjustment for BMI) N=1914 | Model 3 (Model 2 and adjustment for hypertension, diabetes, smoking, QUICKI, excluding insulin use) N=1871 | |||||||
| |||||||||
β -coeff | 95% CI | p-value | β -coeff | 95% CI | p-value | β -coeff | 95% CI | p-value | |
| |||||||||
Ln Testosterone | 0.041 | 0.009 to 0.073 | 0.013 | 0.038 | 0.006 to 0.070 | 0.020 | 0.038 | 0.005 to 0.071 | 0.022 |
Ln Bioavailable Testosterone | 0.028 | -0.000 to 0.056 | 0.053 | 0.024 | -0.005 to 0.053 | 0.107 | 0.018 | -0.013 to 0.048 | 0.255 |
Ln Estradiol | -0.003 | -0.035 to 0.029 | 0.847 | -0.009 | -0.042 to 0.024 | 0.582 | -0.019 | -0.052 to 0.014 | 0.268 |
Ln DHEA | -0.025 | -0.066 to 0.015 | 0.222 | -0.027 | -0.068 to 0.14 | 0.197 | -0.043 | -0.085 to 0.000 | 0.049 |
Ln SHBG | -0.006 | -0.050 to 0.039 | 0.795 | 0.004 | -0.043 to 0.051 | 0.859 | 0.031 | -0.020 to 0.082 | 0.240 |