Table 2.
The deregulated DEGs sharing from cirrhosis to metastasis stage classified by the following screened GO.
| Functional Categories | Number Of Annotated Genes | ||||
| 12th week | 14th week | 16th week | 20th week | 4 group | |
| Metabolism | 334/318 | 403/324 | 541/446 | 494/375 | 206/198 |
| Transport | 162/164 | 188/167 | 264/225 | 229/195 | 101/106 |
| Cell Growth | 129/88 | 161/86 | 207/104 | 218/88 | 89/51 |
| Cell Differentiation | 103/57 | 127/67 | 170/69 | 171/69 | 72/35 |
| Apoptosis | 87/50 | 113/48 | 128/62 | 153/46 | 59/28 |
| Angiogenesis | 12/11 | 15/13 | 23/15 | 25/14 | 9/6 |
| Cell Proliferation | 68/51 | 93/57 | 108/57 | 115/54 | 46/36 |
| Cell Migration | 13/12 | 15/15 | 30/13 | 25/13 | 10/8 |
| Cell Adhesion | 62/25 | 76/30 | 106/30 | 94/30 | 40/13 |
| Extracellular Matrix | 41/21 | 48/22 | 61/29 | 73/23 | 26/14 |
| Oxidative Stress | 31/19 | 41/24 | 43/27 | 50/26 | 23/12 |
| Immune Response | 30/25 | 34/23 | 38/35 | 35/28 | 19/16 |
| Inflammatory Response | 12/17 | 18/20 | 17/31 | 18/21 | 7/11 |
| Cytochrome | 19/30 | 23/28 | 29/45 | 25/38 | 11/20 |
| Signal Transduction | 140/106 | 165/111 | 243/129 | 213/115 | 87/59 |
| Protein Kinase | 114/67 | 128/77 | 193/95 | 185/73 | 65/38 |
| Proteasome | 17/6 | 20/8 | 25/7 | 19/6 | 13/4 |
NOTE: The words '12th week, 14th week, 16th week, 20th week' in the table indicate the cirrhosis tissue, dysplastic nodules, early cancerous nodules and cancerous nodules with metastasis, respectively. The word '4 group' means the DEGs sharing for the above 4 stages of liver tissues. The numbers up and down the line indicate the number of up-regulated and down-regulated DEGs respectively.