Table 5.
The down-regulated DEGs sharing from cirrhosis to metastasis stage relating to the following GO process.
| Gene Symbol | Gene Title | GO |
| C5 | complement component 5 | 1–2 |
| IL4RA | interleukin 4 receptor, alpha | 1–2 |
| MBL2 | mannose binding lectin 2 (protein C) | 1–3 |
| NOX4 | NADPH oxidase 4 | 2–3 |
| ATRN | Attractin | 2–3 |
| C1S | complement component 1, s subcomponent | 1 |
| C4BPB | complement component 4 binding protein, beta | 1 |
| AZGP1 | alpha-2-glycoprotein 1, zinc | 1 |
| C6 | complement component 6 | 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 1 |
| MX2 | myxovirus (influenza virus) resistance 2 | 1 |
| OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46 kDa | 1 |
| RT1-S3 | RT1 class Ib, locus S3 | 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 1 |
| APOA2 | apolipoprotein A-II | 2 |
| BCL6_predicted | B-cell leukemia/lymphoma 6 (predicted) | 2 |
| KLKB1 | kallikrein B, plasma 1 | 2 |
| PROC | protein C | 2 |
| PTGER3 | Prostaglandin E receptor 3 (subtype EP3) | 2 |
| MEOX2 | mesenchyme homeobox 2 | 3 |
| CA3 | carbonic anhydrase 3 | 3 |
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 3 |
| ALAD | aminolevulinate, delta-, dehydratase | 3 |
| CYP2E1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 3 |
| EGFR | epidermal growth factor receptor | 3 |
| HAO1 | hydroxyacid oxidase 1 | 3 |
| HNF4A | Hepatocyte nuclear factor 4, alpha | 3 |
NOTE: The numbers from 1–3 indicate immune reponse, inflammatory response and oxidative stress, respectively.