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. 2009 Aug 4;4:31. doi: 10.1186/1749-799X-4-31

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Copyright © 2009 Yoshida et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pasteurized bone with (MC+; FGF2-) at 4 weeks after grafting shows the grafted bone (left part) and the host bone (right part). Bone formation at the end of the host bone is rather mature (A, B) with osteoclasts on the surface of the bone trabeculae (C, D). Grafted bone characterized by empty lacunae is absorbed and replaced by fibrous tissue (E) associated with osteoclasts on the surface of the pasteurized bone (F). (Original magnification, H&E staining; A; ×70, B; E; ×150, TRAP staining; C; ×70, D; F; ×150).