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. Author manuscript; available in PMC: 2009 Aug 24.
Published in final edited form as: Nat Rev Drug Discov. 2009 Jan;8(1):33–40. doi: 10.1038/nrd2781

Figure 2. NF-κB target genes involved in cancer development and progression.

Figure 2

NF-κB activation affects all six hallmarks of cancer through the transcription of genes involved in cell proliferation, angiogenesis, metastasis, inflammation and suppression of apoptosis as identified in both cell lines and tissue samples (adapted from r ref. 17).