Skip to main content
. Author manuscript; available in PMC: 2009 Dec 26.
Published in final edited form as: Cell. 2009 Jun 26;137(7):1225–1234. doi: 10.1016/j.cell.2009.04.022

Figure 4. Administration of bretazenil into the PBN prevents starvation in mice after ablation of AgRP neurons.

Figure 4

(A) Percentage of initial body weight of DT-treated, AgrpDTR/+ mice after chronic administration of bretazenil in 3 post-synaptic areas of AgRP neurons in the hindbrain (PBN, PAG, and NTS).

(B) Percentage of initial body weight of DT-treateted, AgrpDTR/+ mice after chronic administration of bretazenil in 2 forebrain regions (PVN and LS) with projections from AgRP neurons.

N = 6 – 8 per each group. Error bars represent the SEM.

(C) Coronal illustrations of mouse hindbrain regions; the dots represent effective infusion sites in the PBN area. LC, locus ceruleus; 4v, 4th ventricle.