Figure 5.

BBB opening for ultrasonic transmission frequencies from 5.0 to 8.0 MHz for the same MI_insitu. 20-ms ultrasound pulses repeated at 10 Hz with an F/1.5 focal configuration were transmitted for 30 seconds immediately after a 30-μL Definity injection. The mean and standard deviation for four animals are indicated at each frequency. Non-derated and derated pressures as well as MI $(P_{-0.3}∕\sqrt{f})$ and MI_{in situ} $(P_{\text{in situ}}∕\sqrt{f})$ for each frequency are listed.